Convalescent Plasma for COVID-19 treatment

[HALL85]

Be on the lookout for an announcement on Friday regarding the use of Convalescent Plasma to treat COVID-19 patients that are in ICU's or on ventilators. FDA, BARDA, Red Cross and Community Blood Centers working together to harvest plasma for patient use. It will probably be on the FDA site tomorrow night.

Essentially, those COVID patients that are 28 day post-symptomatic will be asked to donate plasma that will be transfused into hospitalized patients most in need. This treatment has been utilized in China and on a small scale in California and Washington, but to free up critical care beds, FDA is fast tracking the therapy to scale up quickly given the anticipated increase in hospitalizations. Mayo Clinic will hold the IND/IRB for all plasma collections and use, while the Red Cross will serve as a coordinating body with 50+ community blood banks, to ensure that the plasma is tracked and distributed equitably.

The units will be free (figuring out reimbursement on the back end) and there will be a series of public service announcements released as early as next week imploring those recovered COVID-19 patients to donate plasma.

 

[Section112]

Great way to pay it forward to help existing and future patients. The science community is really amazing me with their response to this in so many ways.

 

[NYShoreGuy]

This is a great step, also saw a doc on a netflix presentation believes specific antibodies would give a 8 to 10 week grace period of prevention in lieu of a full time vaccine

 

[HALL85]

Great way to pay it forward to help existing and future patients. The science community is really amazing me with their response to this in so many ways.

FDA also bypassing a number of regulations. This would normally take over a year to accomplish. Dr. Peter Marks from FDA CBER leading the effort.

 

[HALL85]

Great way to pay it forward to help existing and future patients. The science community is really amazing me with their response to this in so many ways.

In addition, one plasma donation can treat two or even three patients, as therapy I believe calls for 200ml.

 

[HALL85]

Will be announced at the White House briefing tomorrow.

 

[NYShoreGuy]

Will be announced at the White House briefing tomorrow.

Trump cant botch this just say our people are putting effort to help our country

 

[HALL85]

Trump cant botch this just say our people are putting effort to help our country

SMH

 

[shu09]

SMH

Amen. People just can't help but to politicize everything. Really sad.

Thanks for the scoop.

 

[NYShoreGuy]

Amen. People just can't help but to politicize everything. Really sad.

Thanks for the scoop.

This is not about dem or rep it is about office of the president and having proper decorum...how can it be argued in his favor that he has projected good rhetoric in this from the top?

 

[shu09]

This is not about dem or rep it is about office of the president and having proper decorum...how can it be argued in his favor that he has projected good rhetoric in this from the top?

That has nothing to do with what HALL85 posted. I think he's done a decent job on this issue, pretty average if you ask me. Some things he has done well, some he could have done better.

Overall he has been a very average president. He has not been the change agent he campaigned as. He's done a bunch of positive things for the country but also made a bunch of missteps. He is the definition of average.

 

[Merge]

I think he's done a decent job on this issue, pretty average if you ask me.

On this issue? Really?

He has been absolutely horrendous on this issue.
It’s not his fault it is here, but he made the problem worse by downplaying it constantly. Saying we have it shut down, saying it was only 15 people and will be down to zero, saying it’s only the flu, yelling at reporters to softball questions (which Pence was able to knock out of the park) his experts constantly correcting what Trump was saying....

Fauci has been great. The rest average... Trump has performed... as expected.

 

[shu09]

On this issue? Really?

He has been absolutely horrendous on this issue.
It’s not his fault it is here, but he made the problem worse by downplaying it constantly. Saying we have it shut down, saying it was only 15 people and will be down to zero, saying it’s only the flu, yelling at reporters to softball questions (which Pence was able to knock out of the park) his experts constantly correcting what Trump was saying....

Fauci has been great. The rest average... Trump has performed... as expected.

Yes, he's been decent on this issue. Stop listening to the twitter TDS mob and the cable news folks.

Trump has been average. Pence has been excellent.

 

[HALL85]

Yes, he's been decent on this issue. Stop listening to the twitter TDS mob and the cable news folks.

Trump has been average. Pence has been excellent.

I think Birx has been outstanding. Mnuchin might be viewed favorably if the checks get out.

 

[Merge]

Yes, he's been decent on this issue. Stop listening to the twitter TDS mob and the cable news folks.

Trump has been average. Pence has been excellent.

I don’t watch cable news. My opinions on Trump are through the lens of watching him. In my personal opinion, his downplaying this made the problem worse. It gave people a reason not to take it seriously. That was a mistake.

All he had to say was that we are still learning, but doing our best to keep you safe. Encourage people to be vigilant, but keep them calm... and then let the experts talk. That would have been average. He made the situation worse.

 

[shu09]

I think Birx has been outstanding. Mnuchin might be viewed favorably if the checks get out.

Yes. I'd say Birx has even been better than Fauci.

 

[shu09]

I don’t watch cable news. My opinions on Trump are through the lens of watching him. In my personal opinion, his downplaying this made the problem worse. It gave people a reason not to take it seriously. That was a mistake.

All he had to say was that we are still learning, but doing our best to keep you safe. Encourage people to be vigilant, but keep them calm... and then let the experts talk. That would have been average. He made the situation worse.

"My administration will take all necessary steps to safeguard our citizens from this threat." -- Trump during the State of the Union speech on February 4.

 

[Merge]

"My administration will take all necessary steps to safeguard our citizens from this threat." -- Trump during the State of the Union speech on February 4.

If those were the only words he uttered on the subject and let the experts take it from there, I might agree with your average assessment.
Unfortunately, he did not stop there and I am including them in my assessment.

Things like
The heat will kill it
We’re down to 5 cases which will be down to 0
It’s going to disappear like a miracle
Asking if a flu vaccine will help
Those infected can get better at work
Responding pathetically about what to say to Americans who are scared...

He has had 2-3 days of good presses conferences / speeches out of about 30.

 

[HALL85]

Having been “under the tent” on the scale-up of convalescent plasma therapy for the past several weeks, I am inspired by the American spirit, just observing federal agencies, the public and private sector working together endless hours, solving problems in real time, beating deadlines toward a common goal. These people are incredible and would do this no matter who is President. I will add that someone (either Trump or someone in his team) has eliminated a large number of regulatory obstacles and other hurdles to rapidly speed up the process. Things that I haven’t seen happen in my 40+ years in this business. Things that the FDA would never, ever do on their own. So in this instance, it’s hard to criticize the administration of responding slowly. If anything, it’s the opposite.

 

[shupat08]

Jan. 22
“We have it totally under control. It’s one person coming in from China, and we have it under control. It’s going to be just fine.” - CNBC Interview

Feb. 10
“Looks like by April, you know, in theory, when it gets a little warmer, it miraculously goes away.” - NH Rally

Feb. 24
“The Coronavirus is very much under control in the USA. … Stock Market starting to look very good to me!” - Trump Tweet

Feb. 28
“It’s going to disappear. One day, it’s like a miracle, it will disappear.” - News Conference

Feb. 28
"One of my people came up to me and said, “Mr. President, they tried to beat you on Russia, Russia, Russia.” That didn’t work out too well. They couldn’t do it. They tried the impeachment hoax. That was on a perfect conversation. They tried anything. They tried it over and over. They’d been doing it since you got in. It’s all turning. They lost. It’s all turning. Think of it. Think of it. And this is their new hoax. But we did something that’s been pretty amazing. We have 15 people in this massive country and because of the fact that we went early. We went early, we could have had a lot more than that. We’re doing great." - SC Rally

March 9
“The Fake News Media and their partner, the Democrat Party, is doing everything within its semi-considerable power ... to inflame the CoronaVirus situation.” - Trump Tweet

March 10
“We’re prepared, and we’re doing a great job with it. And it will go away. Just stay calm. It will go away.” - Meeting with Republican Senators

March 26
“I don’t believe you need 40,000 or 30,000 ventilators. You know, you go into major hospitals sometimes they’ll have two ventilators, and now all of a sudden they’re saying, ‘Can we order 30,000 ventilators?’” - Faux News Interview

 

[shu09]

It will go away at some point. Here in NJ, probably within the next 4-5 weeks.

 

[shupat08]

It will go away at some point. Here in NJ, probably within the next 4-5 weeks.

LOL. Nice cherry picking there. And nice addition of "at some point". Imagine if we shut down 2 weeks earlier? Conversely imagine if the BET & NCAAT continued?

Do those quotes show that he has done a decent job? Particularly... March 26 (Don't need the equipment governors say they need), Feb 28 (Hoax), Feb 24 (CV under control), Feb 10 (it will go away like a miracle - implying nothing needs to be done about it) and Jan 22 (It's fine and under control)?

And those are simply the quotes from a quick search. He said many ridiculous things during his briefings that Fauci almost immediately had to correct.

 

[Merge]

It will go away at some point. Here in NJ, probably within the next 4-5 weeks.

We're only that close because of the stay at home order... Trump downplaying this between Jan through March made it worse across the country.

 

[shu09]

LOL. Nice cherry picking there. And nice addition of "at some point". Imagine if we shut down 2 weeks earlier? Conversely imagine if the BET & NCAAT continued?

Do those quotes show that he has done a decent job? Particularly... March 26 (Don't need the equipment governors say they need), Feb 28 (Hoax), Feb 24 (CV under control), Feb 10 (it will go away like a miracle - implying nothing needs to be done about it) and Jan 22 (It's fine and under control)?

And those are simply the quotes from a quick search. He said many ridiculous things during his briefings that Fauci almost immediately had to correct.

Words don't tell me if someone has or hasn't done a good job. Actions do. His actions have been decent. Not great, not bad. Decent.

 

[shu09]

We're only that close because of the stay at home order... Trump downplaying this between Jan through March made it worse across the country.

In the end, it's up to state and local governments to do what they feel best for their states.

Here in NJ, Murphy has gone too far. It's pretty much a power grab at this point.

 

[shupat08]

Words don't tell me if someone has or hasn't done a good job. Actions do. His actions have been decent. Not great, not bad. Decent.

Words also make people believe it's a Democratic hoax and that it's under control and makes them think the BET and NCAAT should have happened.

As for actions... How do you feel about Trump administration sending ventilators that don't work to California? Or Trump ordering Pence to not call/not answer phone calls from the Governors of Washington and Michigan?

 

[HALL85]

We're only that close because of the stay at home order... Trump downplaying this between Jan through March made it worse across the country.

We can argue this point either way and never agree. Actually, as this plays out, we should all look at countries that experienced high case, hospitalization and mortality rates versus countries that didn't. Why do countries like Hungary, Slovakia, Belarus have minimal numbers, even though they are on a continent that has some of the most horrendous numbers. What factors do we have in common with other countries experiencing higher infection rates. There is plenty of time to go back and either criticize or thank this administration for how they have responded. I don't think it's that clear right now.

And let's face it, at the end of the day, the public will determine if Trump did a good job or not with this election.

 

[NYShoreGuy]

In the end, it's up to state and local governments to do what they feel best for their states.

Here in NJ, Murphy has gone too far. It's pretty much a power grab at this point.

He has been a prudent person so people csnt golf rignt now boo hoo, meanwhile he has to deal with religous folks in lakewood on a daily basis breaking a large gathering order. He has to deal with other clowns hoarding essential products to resale and price gouging while citizens of all ages are perishes at a rate we all did not want to see.

 

[shu09]

Words also make people believe it's a Democratic hoax and that it's under control and makes them think the BET and NCAAT should have happened.

As for actions... How do you feel about Trump administration sending ventilators that don't work to California? Or Trump ordering Pence to not call/not answer phone calls from the Governors of Washington and Michigan?

Seems like that's an issue with the manufacturer of the ventilator. Glad CA was able to get them to be repaired.

Pence has spoken to those governors multiple times. Fake news.

 

[shupat08]

Seems like that's an issue with the manufacturer of the ventilator. Glad CA was able to get them to be repaired.

Pence has spoken to those governors multiple times. Fake news.

You know how to skirt around things very well. You said Pence has called so its fake news. I said Trump told Pence not to call. We are talking about two different things.

Trump said that Pence “calls all the governors. And I tell him, I’m a different type of person, and I say, ’Mike, don’t call the governor of Washington. you’re wasting your time with him... Don’t call the woman in Michigan.”

Fake News? Trump told Pence to not call the Governor of Washington and Michigan. Trumps words from a national press conference. Man you have your head in the sand.

 

[shu09]

He has been a prudent person so people csnt golf rignt now boo hoo, meanwhile he has to deal with religous folks in lakewood on a daily basis breaking a large gathering order. He has to deal with other clowns hoarding essential products to resale and price gouging while citizens of all ages are perishes at a rate we all did not want to see.

People should be able to golf. People should be able to take their dog to a dog park. Nobody is getting or spreading the virus doing those activities.

Funerals should be exempted from the order. That is cruel. You lectured me on empathy yesterday, how about showing some empathy for folks who have lost a loved one during this time? Also, fathers not being allowed in a room when someone gives birth. Family not being allowed to visit dying relatives in the hospitals. This is cruel government overreach.

 

[shu09]

Trump said that Pence “calls all the governors. And I tell him, I’m a different type of person, and I say, ’Mike, don’t call the governor of Washington. you’re wasting your time with him... Don’t call the woman in Michigan.”

That is not an order. An order is an official policy document.

 

[shupat08]

That is not an order. An order is an official policy document.

So is that "decent" way to lead on national television? Or is it just that Trumps words don't matter?

 

[shu09]

So is that "decent" way to lead on national television? Or is it just that Trumps words don't matter?

That's up to individuals to decide. There has been plenty of contact between the White House and governors, even in Michigan and Washington.

 

[SHUHoopsFan]

So is that "decent" way to lead on national television? Or is it just that Trumps words don't matter?

No politicians words matter. Trumps words don't matter. Keep your doctor, save $2500 didn't matter. The system is a joke. It's time for the people to take back the government.

 

[Merge]

No politicians words matter. Trumps words don't matter. Keep your doctor, save $2500 didn't matter. The system is a joke. It's time for the people to take back the government.

I guarantee I can find a post from every poster here regarding what they expect from a president in a time like this, and I bet all of us have thought the words and tone from the president matter. That all of us expect a certain level of leadership. That all of us expect them to be able to move beyond politics for a moment and have candid conversations with Americans when it matters most.

We've lowered the bar so much.

 

[SHUHoopsFan]

I guarantee I can find a post from every poster here regarding what they expect from a president in a time like this, and I bet all of us have thought the words and tone from the president matter. That all of us expect a certain level of leadership. That all of us expect them to be able to move beyond politics for a moment and have candid conversations with Americans when it matters most.

We've lowered the bar so much.

We would all hope words matter, but truthfully it's all about actions not words. I can live with crappy wording and tone if the job gets done.

 

[shupat08]

De Blasio and Cuomo said NY/C will run out of ventilators by early next week. Is the job getting done?

What happened to the National Defense Production Act?

 

[HALL85]

De Blasio and Cuomo said NY/C will run out of ventilators by early next week. Is the job getting done?

What happened to the National Defense Production Act?

Can we revisit this next week to see if that actually happens? Have you heard Gavin Newsome’s assessment? DiBlasio? Trump isn’t the only politician that says irresponsible things. Actions and results matter.

 

[Merge]

We would all hope words matter, but truthfully it's all about actions not words. I can live with crappy wording and tone if the job gets done.

Yeah... I could too.

But I'm sorry, Trump's words mattered here.
He said people could still go to work with this virus. That was absurd based on what we knew of the virus at the time.
People did not take this virus seriously enough and it spread more than it would have if he did.

Trump was worried about how the economic impact would hurt him than how the virus would impact people.